ABSTRACT
Campylobacter jejuni is a common agent of enterocolitis in humans. Campy lobacteriosis has been recognized as a zoonotic disease whose reservoir is the intestinal flora of poultry. The reposition of fluid and electrolytes is the recommended treatment, and antimicrobials are required only in severe and/or in prolonged disease. Given the emergence of resistance to drugs commonly used in the treatment of acute diarrhea, we studied the antimicrobial susceptibility of 73 strains oí Campylobacter jejuni isolated from stool culture. The antimicrobials tested were: erythromycin, azithromycin, ampicillin and ciprofloxacin. Of the 73 strains tested by E-test, 32.4 percent were resistant to ciprofloxacin and 6.4 percent were resistant to ampicillin. Resistance to erythromycin and azithromycin was not detected. The surveillance of antimicrobial resistance of Campylobacter jejuni is important in the evaluation of empirically used antimicrobials in the treatment of bacterial enterocolitis.
Subject(s)
Adolescent , Adult , Aged , Child , Humans , Middle Aged , Young Adult , Anti-Bacterial Agents/pharmacology , Campylobacter jejuni/drug effects , Feces/microbiology , Chile , Campylobacter Infections/microbiology , Microbial Sensitivity Tests , Prospective Studies , Young AdultABSTRACT
Jarcho-Levin syndrome, also known as spondylothoracic dysplasia and characterized by short trunk dwarfism, "crab-like" rib cage, with ribs and vertebral defects; it is not uncommon in Puerto Ricans. Many patients die in early infancy due to respiratory compromise associated to lung restriction and the reported cases emphasize mostly the skeletal malformations associated to the syndrome. We report the autopsy findings in a newborn with isolated Jarcho-Levin syndrome emphasizing pulmonary pathology. He was a pre-term male who died of respiratory failure at three hours old and, autopsy findings confirmed the clinical diagnosis. Internal examination showed hypoplastic lungs with normal lobation. The histological structure appeared normal and relatively mature; the diaphragm showed eventration and unilateral absence of musculature. This case shows the worst spectum of the Jarcho-Levin syndrome: pulmonary hypoplasia not compatible with extrauterine life. Since thoracic restriction is present during the fetal period, the degree of pulmonary hypoplasia probably defines survival beyond the neonatal period.
Subject(s)
Humans , Male , Infant, Newborn , Abnormalities, Multiple/pathology , Spine/abnormalities , Ribs/abnormalities , Dwarfism/pathology , Lung/abnormalities , Apgar Score , Autopsy , Infant, Premature , Radiography, Thoracic , SyndromeABSTRACT
Forty patients (14 women and 26 men; mean age 40 +/- 13 years, range 7 to 60) diagnosed to have idiopathic ventricular tachycardia (right ventricular 28, left ventricular 12) underwent electrophysiologic study and radiofrequency catheter ablation. Echocardiography, signal averaging, magnetic resonance imaging and cardiac catheterisation with angiography were used as indicated to rule out identifiable underlying etiologies. Gross localisation of the area of origin of the ventricular tachycardia from the surface electrocardiogram could be made in all cases. Accurate localisation of the site of origin was done by activation mapping and pace mapping. Radiofrequency application was successful in achieving a cure in 34 (85%) patients, with a mean of 8.3 +/- 4.7 energy applications and a fluoroscopy time of 38 +/- 19 minutes. Unsuccessful cases were characterised by wide and slurred QRS complexes during ventricular tachycardia, possibly indicating a deeper intramyocardial or epicardial site of origin of the tachycardia. Radiofrequency ablation appears to be the treatment of choice for symptomatic idiopathic ventricular tachycardia, having a high success and safety rate.
Subject(s)
Adult , Cardiac Pacing, Artificial , Catheter Ablation , Child , Electrocardiography , Female , Cardiac Catheterization , Heart Conduction System/surgery , Humans , Male , Middle Aged , Tachycardia, Ventricular/diagnosisABSTRACT
Dez cäes da raça Fila Brasileiro, em fase de crescimento, foram utilizados para avaliar o emprego de placas ósseas de cloreto de polivinila no tratamento de fraturas completas do terço distal do rádio e da ulna. Näo foram utilizados meios externos de imobilizaçäo. Clinicamente, os animais näo mostraram quaisquer anormalidades durante o período de observaçäo. A consolidaçäo da fratura, evidenciada radiologicamente, ocorreu dentro do tempo esperado